Senior Scientist, I

Company: AbbVie
Location: South San Francisco
Posted on: March 5, 2026

Job Description:

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Job Description Description: The Biologics Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept across both liquid and lyophilized presentations. We have an exciting opportunity for a Senior Scientist I to join our team at our Bay Area site in South San Francisco, CA to lead end to end formulation and process development. In this role, you will plan and execute DoE driven studies, assess clinical in-use stability, and model degradation pathways. You will establish fit-for-purpose analytical strategies using protein characterization and stability methods such as SEC, CE-SDS, icIEF, HIAC, MFI, and DLS. A core focus of the role is building efficiency in drug product manufacturing process operations at scale by devising, deploying and optimizing high throughput automated workflows to increase scientific depth and speed across a matrixed, cross-site environment. KEY RESPONSIBILITIES INCLUDE: Develop stable and fit-for-purpose liquid and lyophilized drug products through the design and execution of formulation, process development, and clinical in-use studies. Support testing of representative stability lots to support drug substance and drug product shelf-life extension. Generate high-quality data based on sound scientific principles and document results in electronic lab notebook. Responsible for accumulating and organizing experimental and other relevant data, making appropriate recommendations for analyzing and interpreting results, and effectively communicating finds to various audiences in scientific presentations, technical reports, and regulatory documents Formulate conclusions and design follow-on experiments based on multidisciplinary data. Drive innovation and continuously enhance capabilities and business processes within the organization. Initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program. Work efficiently and collaboratively in an agile team setting with minimal direction from supervisors. Represent the function within cross-functional and cross-site technical teams. Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, and GxP compliance where applicable. Qualifications Ph.D. in chemical engineering, pharmaceutical sciences, material science, analytical sciences or equivalent field with 0-3 years of experience or BS/MS degree with 8-10 years of relevant experience in the biotechnology or pharmaceutical industry. Strong technical background in protein formulation principles, drug product degradation pathways, drug product lyophilization, drug product manufacturing process unit operations and characterization approaches. Hands-on experience in analytical techniques used for protein characterization and stability testing preferred (e.g., SEC, CE-SDS, icIEF, HIAC, MFI, DLS, etc.). Technical experience with developing fit-for-purpose analytical characterization techniques is desired. Prior experience in the development of protein product formulations is highly desirable. Detail-oriented and highly organized with a demonstrated ability to drive innovative science and solve complex problems. Excellent communication and written skills Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible toparticipatein our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's soleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

Keywords: AbbVie, Arden-Arcade , Senior Scientist, I, Science, Research & Development , South San Francisco, California